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Windows of Susceptibility Studies

The investigators for the Breast Cancer and the Environment Research Program (BCERP) Windows of Susceptibility studies are pursuing novel experimental and ancillary epidemiological, clinical, or population studies involving human subjects focusing on the gene-environment interactions as well as molecular mechanisms of environmental influences on breast cancer risk operational during relevant windows of susceptibility over the life span of an organism. Investigators have partnered with breast cancer advocate(s) and/or members of the engaged community to facilitate bi-directional communication. Responsibilities of the community partners include communicating community concerns regarding environmental exposures of high and relevant importance, representing the community perspective when investigators are designing their studies, and helping to translate and communicate study findings to community members, policy makers, and/or other stakeholders, as appropriate.

The Principal Investigator (PI) and lead representative for the Community Partners (CP) for each study site is listed below. Click on the project titles to view a summary of each study.

Michigan State University Pubertal High Fat Diet: Effects on Inflammation, Mammary Development and Cancer
co-PIs: Sandra Z. Haslam, PhD, and Richard Schwartz, PhD
CP Rep: Evelyn Barrack,Michigan Breast Cancer Coalition
Mount Sinai School of Medicine Breast Cancer Genomics in Windows of Susceptibility to Endocrine Disruptors
co-PIs: Susan L. Teitelbaum, PhD, and Jia Chen, ScD
CP Reps: Karen Miller, Huntington Breast Cancer Action Coalition, Inc. and Laura Weinberg, Great Neck Breast Cancer Coalition
Public Health Institute & Columbia University PEDIGREE: Prenatal Environmental Determinants of InterGenerational Risk
Co-PIs: Barbara A. Cohn, PhD and Mary Beth Terry, PhD
CP Rep: Marj Plumb, DrPH, Plumbline Coaching and Consulting
University of Alabama at Birmingham Combinational Environmental Chemicals Altering Susceptibility for Mammary Cancer
PI: Coral Lamartiniere, PhD
CP Reps: Beverly Laird and Rebecca Di Piazza Rawson, Susan G Komen for the Cure, North Central Alabama Affiliate
University of California
San Francisco
Environmental Effect on the Mammary Gland across the Lifespan
PI: Zena Werb, PhD
CP Rep: Janice Barlow, RN, Zero Breast Cancer
University of Cincinnati Susceptible Window of High Fat Diet/Bisphenol A Programming of Breast Cancer Risk
PI: Shuk-Mei Ho, PhD
CP Rep: Tracie Metzger, Pink Ribbon Girls
University of North Carolina Chapel Hill Pregnancy, Obesogenic Environments, and Basal-like Breast Cancer
PI: Melissa A. Troester, PhD
CP Rep: Neasha Graves, UNC Chapel Hill Gillings School of Global Public Health
University of Wisconsin Madison Genetics of Breast Cancer Risk at Windows of Exposure
PI: Michael N. Gould, PhD
CP Rep: Mary Pat Berry